Ondansetron Injection IP - BRINON Injection

BRINON Injection – Trusted Antiemetic for Comprehensive Nausea & Vomiting Relief

BRINON Injection – The composition of Ondansetron Injection IP is an antiemetic medication used to manage nausea and vomiting.
It works by acting both centrally and peripherally by blocking 5-HT3 receptors in the area postrema in the brain and depressing the chemoreceptor trigger zone (CTZ) that helps in medicating the sensation of nausea and vomiting.
Peripherally, it antagonizes 5-HT3 receptors found on vagus nerve terminals which transfer signals to the brain and transmit a sensation of nausea and vomiting.
Thus, it helps prevent and manage nausea sensation through dual action—centrally and peripherally—by antagonism of 5-HT3 receptors.

Key Benefits of Ondansetron Injection IP – BRINON Injection
✅ First-line therapy: For the management of chemotherapy and radiation therapy-induced nausea.
✅ FDA-approved: For the prevention and treatment of nausea induced by chemotherapy, radiation therapy, and post-operative nausea. It acts centrally (depressing CTZ) and peripherally (on vagus nerves in GI tract) to prevent and manage nausea and vomiting.
✅ Availability in multiple dosage: Available in different forms such as dispersible tablets, drops, and injections, enhancing dose flexibility and improving patient compliance.

Recommended By Specialists:
👨‍⚕️ General Physicians: It should be used to prefer to treat this combination which is mainly used for symptomatic relief of vomiting due to infections, migraine, or medication side effects.
👨‍⚕️ Oncologists: Mainly used to prevent chemotherapy-induced nausea and vomiting (CINV).
👨‍⚕️ Gastroenterologists: Mainly prescribed for nausea and vomiting due to acute gastroenteritis, hepatitis, or gastrointestinal procedures.

INDICATIONS:
✅ Nausea, vomiting in gastroenteritis
✅ Chemotherapy-induced nausea & vomiting
✅ Radiation therapy-induced nausea & vomiting
✅ Post-operative nausea & vomiting